## Section 1: Ingredients ### 1. Symbiota™ 020 - **Format/Dosage:** Clinically-validated multi-strain postbiotic (liquid and powder compatible). - **Target Indication:** Gut barrier restoration, immune modulation, and targeted IBD/colitis support in advanced gastrointestinal formulations. - **Core Mechanisms & Clinical Highlights:** - *Gut Barrier Restoration*: Preserves intestinal tight junction proteins (ZO-1 and Occludin) to prevent leaky gut syndrome. - *Immune Modulation*: Balances gut-immune response by modulating pro-inflammatory cytokines (IFN-γ, IL-1β, IL-12). - *Stability & Delivery*: Highly stable, developed via patented precision symbiotic fermentation, delivering a microbial metabolite matrix without live bacteria. ### 2. Symbiota™ 901 - **Format/Dosage:** Multi-strain postbiotic ingredient targeting the gut-metabolic axis. - **Target Indication:** Metabolic health, glucose metabolism support, and GLP-1 signaling regulation. - **Core Mechanisms & Clinical Highlights:** - *GLP-1 Stimulation*: Clinically proven to significantly increase GLP-1 secretion, supporting glucose homeostasis and appetite regulation. - *HbA1c Stabilization*: Human trials show 75% of metformin-resistant individuals achieved stable or reduced HbA1c levels. - *IMP Reduction*: Decreases Imidazole Propionate (IMP)—a microbial marker linked to insulin resistance—by 52% to manage metabolic syndrome. ### 3. Symbiota™ 191 - **Format/Dosage:** Multi-strain, nano-sized postbiotic/metabiome matrix for pediatric applications. - **Target Indication:** Endocrine balance, puberty timing modulation, and gut-brain-hormone axis regulation in children. - **Core Mechanisms & Clinical Highlights:** - *Microbiome Rebalancing*: Enriches beneficial microbiota and increases α-diversity to counteract dysbiosis linked to early hormonal triggers. - *Hormonal Normalization*: Clinically validated to regulate Luteinizing Hormone (LH) and Estradiol (E2) levels, supporting age-appropriate development. - *Safety Profile*: Provides a highly stable, safe, and natural pediatric intervention. ### 4. Symbiota™ 701 - **Format/Dosage:** Precision microbiome active cosmetic ingredient (Global & China INCI compliant). - **Target Indication:** AhR-targeted skin microbiome regulation, skin barrier repair, and soothing reactive skin. - **Core Mechanisms & Clinical Highlights:** - *AhR Pathway Activation*: Acts directly on the Aryl Hydrocarbon Receptor (AhR) to coordinate cellular skin repair and calm inflammatory responses. - *Barrier Integrity*: Significantly reduces Trransepidermal Water Loss (TEWL) and improves barrier integrity in compromised skin, including atopic dermatitis and plaque psoriasis. - *Formulation Flexibility*: Highly stable for acne-prone, oily, or reactive skincare formulations. ### 5. Symbiota™ 217 - **Format/Dosage:** Multi-strain precision-fermented postbiotic/metabiotic ingredient. - **Target Indication:** Liver detoxification, gut-liver axis regulation, and reduction of metabolic liver dysfunction. - **Core Mechanisms & Clinical Highlights:** - *Endotoxin Load Reduction*: Reinforces the intestinal barrier, preventing gut-derived toxins from causing systemic inflammation. - *Liver Support*: Proven in NASH animal models and human microbiome analysis to significantly reduce inflammatory signaling associated with liver stress. - *Microbiota Reshaping*: Promotes beneficial bacteria (e.g., *Roseburia hominis*) to increase short-chain fatty acid (SCFA) production. ### 6. NEXOSOME™ - **Format/Dosage:** Next-Generation Probiotic (NGP) derived exosome fluid (Standardized concentration of ≥1 Trillion EVs/mL). - **Target Indication:** Skin barrier repair, anti-aging, cell rejuvenation, and advanced cosmetic formulations. - **Core Mechanisms & Clinical Highlights:** - *Advanced Absorption*: Delivers ultra-small nano-scale vesicles to accelerate skin absorption for rapid renewal. - *Rapid Re-epithelization*: Outperforms traditional probiotic-derived and human umbilical cord matrix stem cell (hucMSC-EVs) exosomes in promoting wound healing in human keratinocytes. - *Antioxidant & Anti-inflammatory*: Enhances SOD, CAT, and GSH antioxidant activities against UV stimulation; inhibits pro-inflammatory cytokines (IL-1, IL-6, TNF). --- ## Section 2: Turnkey Products ### 1. Probiome 3-in-1 Powder Sachet - **Format/Dosage:** Powder Sachet (6g/sachet, 30 sachets/box). - **Target Indication:** Covers 12 physiological benefits including gastric protection, intestinal conditioning, immune regulation, and allergy relief. - **Core Bioactives:** 12 probiotic strains delivering 20 billion live bacteria per sachet (meeting the recommended daily intake of $>10$ billion). - **Mechanism of Action:** - *Lactobacillus acidophilus*: Reduces the risk of gastric ulcers. - *Streptococcus thermophilus*: Improves gastrointestinal discomfort and lactose intolerance. - *Bifidobacterium brevis* & *Bifidobacterium breve*: Prevents diarrhea and promotes bowel movements. - *Lactobacillus paracasei* & *Lactobacillus leimannii*: Regulates immunity and improves allergies. - **Technology & Protection:** Triple-layer crystal sphere protection technology to resist gastric acid and bile salts, ensuring live bacteria reach the intestines. ### 2. BonePro Ca++ - **Format/Dosage:** Powder Sachet (5.5g/sachet, 30 sachets/box). - **Target Indication:** Calcium and vitamin D supplementation for supporting bone and overall health. - **Core Bioactives:** Irish Organic Seaweed Calcium (sourced from red algae in unpolluted waters) combined with Natural Buckwheat-Sourced D3 (100% vegetarian) and inulin. - **Mechanism of Action:** - *Irish Organic Seaweed Calcium*: Boasts an absorption rate up to 39.4%, significantly superior to common calcium carbonate and other common calcium sources. - *Natural Buckwheat-Sourced D3*: Scientifically cultivated to support bone development and maintain blood calcium balance. - *Calcium + Inulin Synergy*: Animal and clinical studies have shown that combining calcium with inulin increases bone density. ### 3. V-ProtecPro - **Format/Dosage:** Capsule (485mg/capsule, 100 capsules/box). - **Target Indication:** Supports immune function and helps reduce the risk of viral and cold infections. - **Core Bioactives:** Vitamin C (250mg/capsule) and Honeysuckle extract (rich in chlorogenic acid and MIR2911). - **Mechanism of Action:** - *Dual Action*: Vitamin C activates immune cells and accelerates viral phagocytosis, while honeysuckle effectively inhibits viral replication and forms a protective barrier. - *Vitamin C*: Activates phagocytes and white blood cells, accelerating the phagocytosis of foreign substances and strengthening the immune system. - *Honeysuckle extract*: Rich in chlorogenic acid and MIR2911, showing the potential of antiviral effects. - **Scientific & Experimental Evidence:** - Experimental evidence suggests that chlorogenic acid can protect cells and block SARS virus infection. - Latest research proves that MIR2911 can inhibit the replication of coronavirus. ### 4. Probiome Herbal+ - **Format/Dosage:** Capsule (455mg/pc, 120pcs/bottle/box). - **Target Indication:** Dual Benefits: Supports Liver Health (helps reduce plasma GOT/AST and GPT/ALT values) and helps prevent colorectal cancer (reduce the incidence of colorectal cancer). - **Core Bioactives:** Patented Symbiota® postbiotic MS-20 combined with a five-ingredient herbal formula (curcumin, grape seed, spirulina, catechins, and antrodia cinnamomea). - **Mechanism of Action:** - *Patented Symbiota® MS-20*: Balances the gut microbiome, supports intestinal mucosal repair, and maintains a balanced intestinal flora. - *Herbal Formula Matrix*: Reduces chronic inflammation and intestinal stress. - *Metabolic & Lipid Regulation*: Regulates hepatocyte lipid metabolism, reduces fat deposition, and potentially helps with non-alcoholic fatty liver disease (NAFLD). - *Antioxidant Pathway*: Increases the activity of three major liver antioxidant enzymes (SOD↑, CAT↑, GPX↑). - **Scientific & Clinical Evidence:** - *Liver Protection*: Animal and cell-based studies show it effectively lowers serum ALT and AST levels, alleviates liver function abnormalities, reduces AST/GPT, and increases albumin. - *Colorectal Cancer Efficacy*: Phase II clinical trials show MB-6 significantly improves Overall Survival (OS) in colorectal cancer patients. ### 5. VisionPro Lutein Shot - **Format/Dosage:** Liquid Sachet (15ml/sachet, 12 sachets/box). - **Target Indication:** Lutein supplementation for relieving eye fatigue and improving visual clarity. - **Core Bioactives:** Patented free-type lutein (8mg of lutein per sachet), Zeaxanthin, and Dual Anthocyanin Matrix (Bilberry and Blackcurrant extracts rich in polyphenols and various anthocyanins). - **Mechanism of Action:** - *Patented Free-Type Lutein*: Utilizes CO₂ supercritical extraction and microencapsulation technology for high purity, excellent stability, and superior absorption rate compared to standard esterified lutein. - *Dual Anthocyanin Matrix*: Relieves eye fatigue and improves clarity through antioxidant-rich polyphenols and anthocyanins. - **Formulation Feature:** Formulated without artificial coloring agents or flavorings. - **Scientific & Clinical Evidence:** - *JAMA Study Reference*: A JAMA study indicates that 6mg of lutein daily can reduce the risk of macular degeneration by 43% (this product provides 8mg of lutein per sachet). ### 6. GlowUp Iron+ - **Format/Dosage:** Tablet (225mg per film-coated tablet, 28 tablets/box; small tablet design, easy to swallow, and free of rusty taste). - **Target Indication:** Helps reverse low iron levels and helps with red blood cell formation (effectively improving iron deficiency anemia). - **Core Bioactives:** Ferrous glycinate (iron with high bioavailability), Vitamin C, Folic acid, and Vitamin B12. - **Mechanism of Action:** - *Ferrous glycinate*: 3.5 times more bioavailable than ferrous sulfate, US GRAS certified; provides higher absorption and less gastric upset. - *Vitamin C*: Promotes iron absorption. - *Folic acid + Vitamin B12*: Multivitamin addition that aids in red blood cell formation. - **Scientific & Clinical Evidence:** - *Clinical Data (120 children, 1 month)*: Demonstrated an average increase of 15 g/L in hemoglobin. - *Safety Profile*: Clinically proven and verified in multiple studies to be gentle on the stomach and intestines, with a lower side effect rate than traditional iron supplements. ### 7. Probiome Digest+ - **Format/Dosage:** Liquid Sachet (15ml/sachet, 30 sachets/box). - **Target Indication:** Increase bowel movements, improve gut flora ecology, maintain healthy digestive function, and promote smooth bowel movements. - **Core Bioactives:** Symbiota® postbiotic MS-20 (nano-grade fermentation extract) and natural plant fermentation extracts. - **Mechanism of Action:** - *Symbiota® postbiotic MS-20*: Balances gut microbiome and acts as a globally patented product that directly nourishes healthy intestinal bacteria. - *Natural Plant Fermentation Extracts*: Rich in antioxidants to promote metabolic balance. - *Absorption & Routine*: Nano-grade small molecule essence for more immediate absorption; take one packet daily to help you build your own ecosystem of good bacteria. ### 8. Probiome Grow+ - **Format/Dosage:** Liquid Sachet (15ml/sachet, 14 sachets/box). - **Target Indication:** Targeting Gut Microbiota and Reproductive Hormones regulation; a precision postbiotic product for Precocious Puberty. - **Core Bioactives:** Symbiota® postbiotic 191 blended with monoammonium glycyrrhizate. - **Mechanism of Action:** - *Symbiota® postbiotic 191*: Improves the gut microbiome. - *Combined Formula Matrix*: Helps regulate sex hormone secretion by improving gut flora. - **Scientific & Experimental Evidence:** - *Animal Testing*: Symbiota® 191 + monoammonium glycyrrhizate effectively influences sex hormone secretion (Luteinizing Hormone / LH, Estradiol / E2), extending growth and development potential. ### 9. Probiome GlucoBalance - **Format/Dosage:** Liquid Sachet (15ml/sachet, 20 sachets/box; sugar-free formula utilizing erythritol and organic stevia extract for more stable blood sugar levels). - **Target Indication:** Blood Glucose Management (helps reduce fasting blood glucose and improves insulin resistance). - **Core Bioactives:** Symbiota® postbiotic 901, yeast chromium, erythritol, and organic stevia extract. - **Mechanism of Action:** - *Symbiota® postbiotic 901*: Improves the gut microbiome, strengthens the intestinal barrier, improves blood sugar regulation, and increases the proportion of beneficial bacteria. - *Yeast Chromium Matrix*: Combined to maintain normal carbohydrate metabolism. - **Scientific & Clinical Evidence:** - *Animal Studies*: Significantly reduced fasting blood sugar, improved insulin resistance, and enhanced blood sugar tolerance. - *Human Studies (12 Weeks)*: 75% of diabetic patients achieved stable or improved blood sugar levels; demonstrated significantly reduced glycated hemoglobin ($HbA1c$) and enhanced the effectiveness of metformin. ### 10. Probiome Max - **Format/Dosage:** Dropper formulation (available in 90ml/bottle/box and 180ml/bottle/box). - **Target Indication / Health Food Certifications:** Formulated for Triple Health Food Certifications: 1. Improves Gut Function 2. Enhance Original Immunity 3. Blood Lipid Regulation - **Core Bioactives:** Patented Symbiota® Fermentation matrix (GRAS certified in the US). - **Mechanism of Action:** - *Patented Symbiota® Fermentation*: Undergoes 4.5 months of long-term maturation to simulate the intestinal environment, preserving beneficial bacterial metabolites. - *Postbiotic Stability*: Postbiotics are stable and safe, unrestricted by live bacterial colonization. - **Scientific & Quantitative Evidence:** - *Microbiome Modulation*: A 9 mL serving is clinically/experimentally shown to increase gut probiotics by up to 5,000 times. - *Safety Profile*: Holds globally recognized international safety certification, including US GRAS certification. ### 11. GlucoBiome Shot - **Format/Dosage:** Liquid Sachet (25 ml/liquid sachet, 20 sachets/box). - **Target Indication:** Glucose Control, supporting gut microbiome balance, management of post-meal glucose spikes, sugar craving control, insulin sensitivity improvement, and overall glycemic stability. - **Core Bioactives:** Symbiota™ 901 postbiotic, *Gymnema sylvestre* extract, chromium, and dietary fiber. - **Mechanism of Action:** - *Microbiome-Driven Glucose Balance*: Powered by Symbiota™ 901 postbiotic to support a healthier gut environment and promote microbiome balance linked to glucose regulation and metabolic stability. - *Botanical Sugar-Metabolism Support*: Incorporates *Gymnema sylvestre* to support healthy glucose metabolism and manage sugar utilization. - *Precision Metabolic Nutrient System*: Combines chromium and dietary fiber to support normal macronutrient metabolism, stabilize blood sugar fluctuations, and enhance metabolic flexibility. ### 12. MetaBiome GLP Recovery - **Format/Dosage:** Powder Sachet (7 g/sachet, 30 sachets/box). - **Target Indication:** For Post-GLP-1 Maintenance, supporting gut microbiome balance, appetite control support, carbohydrate absorption control, essential nutrient support, and metabolic stability maintenance. - **Core Bioactives:** Symbiota™ 901 postbiotic, Glucomannan, White Kidney Bean extract, Branched-Chain Amino Acids (BCAA), Vitamin B complex, Zinc, and Vitamin D3. - **Mechanism of Action:** - *Postbiotic Microbiome Support for GLP-1 Transition*: Powered by Symbiota™ 901 postbiotic to support microbiome balance during GLP-1 therapy, helping to extend metabolic benefits for 4 weeks after discontinuation. - *Satiety & Weight Management Synergy*: Incorporates glucomannan and white kidney bean extract to support satiety and carbohydrate metabolism; glucomannan aids weight loss alongside a calorie-controlled diet. - *Precision Nutrient Recovery System*: Combines BCAA, vitamin B complex, zinc, and vitamin D3 to support muscle maintenance, energy metabolism, and immune function during GLP-1 therapy. ### 13. Tri-Probiome - **Format/Dosage:** Capsule (495mg/capsule, 90 capsules/bottle; formulated capsule for convenient intake and improved dispersion). - **Target Indication:** For Gut Health, supporting microbiome diversity, digestive and immune health, and gut ecosystem balance. - **Core Bioactives:** Complete 3-in-1 Biotics System combining Prebiotics (Natural Soluble Dietary Fiber), Probiotics (15 strains delivering 5B active bacteria per 3 capsules), Postbiotics (Symbiota™ 020), and Biotin. - **Mechanism of Action:** - *Postbiotic Microbiome Foundation (Symbiota™ 020)*: Backed by 9 papers and 23 patents; reshapes the gut microbiome, repairs the gut barrier, balances the immune system, and provides a stable microbiome foundation for digestive and immune health. - *Probiotic Matrix*: Contains 15 kinds of probiotics designed to be resistant to gastric acid to ensure they reach the gut. - *Prebiotic Matrix*: Natural soluble dietary fiber that feeds probiotics, enhances probiotic function, and supports long-term gut microbiome health. - *Nutrient Delivery Support*: Contains biotin, which contributes to the maintenance of normal mucous membranes and supports gut barrier health. ### 14. ActiBiome Daily Nutrition - **Format/Dosage:** Powder Sachet (6.5g/sachet, 30 sachets/box). - **Target Indication:** For Comprehensive Nutrition, supporting 10 Key Body Functions: Gut, Immune, Cardiovascular, Muscular, Skeletal, Skin, Brain, Hormonal, Hydration, and Eye. - **Core Bioactives:** Postbiotics (Symbiota™ 020), 4 Green Botanicals (including inulin, barley grass, and spirulina), and 14 Essential Vitamins & Minerals. - **Mechanism of Action:** - *Postbiotic Gut Restoration Foundation (Symbiota™ 020)*: Backed by 9 papers and 23 patents; reshapes the gut microbiome, repairs the gut barrier, supports nutrient absorption efficiency, strengthens the intestinal environment, and promotes digestive resilience. - *Comprehensive Nutrient Absorption System*: Combines 14 kinds of vitamins and minerals designed to support efficient nutrient utilization and metabolic balance. - *Greens & Prebiotic Synergy for Gut Health*: Utilizes a combination of inulin, barley grass, and spirulina to provide prebiotic fiber and plant nutrients, supporting gut ecology, digestion, and daily nutritional intake.