1.Date of occurrence of the event:2022/08/29

2.Cause of occurrence:Proceeded according to the notice

from Listing Supervision Department of Taipei Exchange

3.Financial and business information:

(1)Monthly

Account                                                        2022/7                2021/7                YoY increase/

                                                                                                                                      decrease (%)

———————————————————————————————————————————

Operating revenue(million)                               130                      158                          -17.7%

Income before income tax(million)                    -79                     -231                            65.8%

Consolidated Net Income Attributed

to Stockholders of the Company(million)           -67                    -196                            65.8%

Earnings per share(dollar)                              -0.13                   -0.39                             66.7%

(2)Accumulated over the last 2 months

Account                                                        2022/6-                 2021/6-                 YoY increase/

                                                                     2022/7                 2021/7                decrease (%)

———————————————————————————————————————————

Operating revenue(million)                                 265                     339                          -21.8%

Income before income tax(million).                   -177                       53                         -434.0%

Consolidated Net Income Attributed

to Stockholders of the Company(million)           -140                      68                          -305.9%

Earnings per share(dollar)                                -0.27                   0.14                          -292.9%

(3)Quarterly

Account                                                                  Q2                          Q2                   YoY increase/

                                                                        2022                     2021                 decrease (%)

———————————————————————————————————————————-

Operating revenue(million)                               483                       487                            -0.8%

Income before income tax(million)                  -534                      -895                           40.3%

Consolidated Net Income Attributed

to Stockholders of the Company(million)         -561                      -813                          31.0%

Earnings per share(dollar)                              -1.10                      -1.64                          32.9%

(4)Accumulated over the last 4 quarters

Account                                                                                    From Q3 of 2021 to Q2 of 2022

———————————————————————————————————————————-

Operating revenue(million)                                                                                               1,788

Income before income tax(million)                                                                                      439

Consolidated Net Income Attributed

to Stockholders of the Company(million)                                                                                  644

Earnings per share(dollar)                                                                                                         1.27

4.Any material information that needs to be specified

  according to Article 4 of Taipei Exchange Procedures

  for Verification and Disclosure of Material Information

  of Companies with TPEx Listed Securities:

  The subjects of the material information announced by the Company in the last

  six business days during August 19, 2022 to August 26, 2022 is as following

  details for the shareholders’ reference.

  Microbio (Shanghai) submitted an IND to US FDA for a phase I clinical

  trial on the broad-spectrum anti-SARS-CoV-2 siRNA (SNS812) co-developed

  with Oneness

5.Any material information in a press conference listed

  under Article 11 of Taipei Exchange Procedures for

  Verification and Disclosure of Material Information of

  Companies with TPEx Listed Securities:None.

6.Any other matters that need to be specified:

  (1)The aforementioned financial information for June 2022 and July 2022 and

       its YOY comparison consists of the reviewed amounts prepared by the

      Company adopting the IFRS, and has not been audited (reviewed) by any

      CPA; it is only for investors’ reference.

  (2)The information for the last quarter (Q2 2022) refers to quarterly

       amounts, and has been reviewed by CPAs.

  (3)The information accumulated over the last 4 quarters consists of the

       consolidated amounts from Q3 2021 to Q2 2022 prepared by the Company

       adopting the IFRS, and has been reviewed by CPAs.

  (4)The investment loss accounted for using the equity method is TWD 61

       million which has been recognized in July 2022.

       The investment loss accounted for using the equity method is TWD 197

       million which has been recognized in July 2021.

  (5)The investment loss accounted for using the equity method is TWD 89

       million which has been recognized in June 2022.

       The investment gain accounted for using the equity method is TWD 260

       million which has been recognized in June 2021.